Cannabinoid Therapy: A New Treatment Pathway
The rise of cancer patients using cannabis for effective treatment and symptom management has shown significant promise for new therapeutic pathways in oncology.
Though studies are only now emerging, the earliest cases (dating to 1998) have begun to build a case for the use of cannabinoids in tumor and cancer treatments with success. These treatments use a fundamentally different approach to inducing cell apoptosis (cell death) and inhibiting angiogenesis, the creation of blood cells that feeds a tumor’s growth.
As always, we are not medical doctors and cannot give medical advice. We recommend consulting with your physician before using any cannabis products for cancer and tumor symptom and case management.
PPARS: The Proliferation Treatment Pathway
PPARs (peroxisome proliferator activated receptors) are a group of nuclear receptor proteins that are essential roles in the regulation of cellular differentiation, development, metabolism and tumorigenesis (the creation of cancer and tumor cells) of higher organisms.
CBD activates the PPAR-gamma group to produce an anti-proliferative effect on tumor and cancer cells, effectively reducing their ability to grow throughout the body. PPARs additionally have a potential benefit as a treatment pathway for the plaque that causes Alzheimer’s disease and the metabolization issues that are responsible for Diabetes.
The location of these receptors throughout the body allows cannabidiol to be an effective treatment for tumors and cancers that have metastasized. Treatments have been proven to induce tumor regression in human lung cancer cell lines.
The ID-1 Gene & Metastasis
The ID-1 gene is still not as well understood as we would like, but is shown to turn off after embryonic development is complete. In several cases of aggressive cancer, the ID-1 gene turns back on and causes malignant cells to invade and metastasize.
Cannabidiol have been shown by Dr. Sean McAllister, a scientist at the Pacific Medical Center in San Francisco, to silence ID-1 expression, showing a new pathway for treatment.
THC & The Entourage Effect
The benefits of cannabis in cancer and tumor management doesn’t end with cannabidiol (CBD) – the use of THC and terpenes can prove to be powerful additions.
THC has shown it’s own unique ability to induce cell apoptosis and slows tumor growth in their Harvard studies. Though often using levels that are far exceeding the 0.3% THC allowed in hemp plants, there is promise that the small amounts found in hemp can additionally have therapeutic promise for cancer and tumor treatment.
Additionally, terpenes that are produced in cannabis plants can have powerful analgesic, anti-inflammatory and mood altering effects that can play a role in symptom management for many patients.
Finally, CBD can help patients manage the symptoms they face with cancer and tumor treatments, including pain, appetite and more.
Improving the quality of life for those struggling with cancer and tumor symptoms is one of the largest goals with cannabis treatments. Finding a doctor that will work with your desired treatment program and help you achieve health is crucial to a successful treatment plan.